[Experimental value of the biliary excretion of the conjugated form of SBP by the in vivo liver and by the isolated and perfused liver].

We first studied the uptake and excretion of the dye BSP by the isolated and perfused rat liver and by the rat liver in vivo. We then studied BSP-glutathion conjugation with these same methods. We found that benziodarone which induces a marked decrease of conjugation is able to inhibit in vitro the combination BSP-glutathion.