[溶菌酶对抗生素的增效作用]
[Potentialization of antibiotics by lytic enzymes].
作者信息
Brisou J, Babin P, Babin R
出版信息
C R Seances Soc Biol Fil. 1975;169(3):660-4.
PMID:129213
Abstract
Few lytic enzymes, specially papaine and lysozyme, acting on the membrane and cell wall structures facilitate effects of bacitracine, streptomycine and other antibiotics. Streptomycino resistant strains became sensibles to this antibiotic after contact with papaine and lysozyme. The results of tests in physiological suspensions concern only the lytic activity of enzymes. The results on nutrient medium concern together lytic, and antibiotic activities.
摘要
一些裂解酶，特别是木瓜蛋白酶和溶菌酶，作用于细胞膜和细胞壁结构，可增强杆菌肽、链霉素和其他抗生素的效果。对链霉素耐药的菌株在与木瓜蛋白酶和溶菌酶接触后对这种抗生素变得敏感。在生理悬浮液中的测试结果仅涉及酶的裂解活性。在营养培养基上的结果涉及裂解活性和抗生素活性。
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