Kim Young Mi, Lee Yoon Jin, Nam Sang Ook, Park Su Eun, Kim Ji Yoen, Lee Eun Yup
Department of Pediatrics, College of Medicine, Pusan National University, Busan, Korea.
J Korean Med Sci. 2003 Aug;18(4):592-4. doi: 10.3346/jkms.2003.18.4.592.
A 13-yr-old female was admitted to our hospital with fever, seizure, and cervical lymphadenopathy. Laboratory data showed pancytopenia, elevation of serum transaminase, lactate dehydrogenase, triglyceride, and ferritin levels. Lymph node biopsy revealed features of Kikuchi's disease and there were signs of histiocytosis and hemophagocytic phenomenon in bone marrow. She recovered after treatment with intravenous immunoglobulin and corticosteroids therapy. Hemophagocytic syndrome can be associated with Kikuchi's disease especially in childhood and seems to have a less aggressive clinical course and better prognosis.
一名13岁女性因发热、癫痫发作和颈部淋巴结肿大入院。实验室检查显示全血细胞减少，血清转氨酶、乳酸脱氢酶、甘油三酯和铁蛋白水平升高。淋巴结活检显示为菊池病特征，骨髓中有组织细胞增多症和噬血细胞现象。经静脉注射免疫球蛋白和皮质类固醇治疗后康复。噬血细胞综合征可与菊池病相关，尤其是在儿童期，其临床病程似乎侵袭性较小，预后较好。
