Van Houtte Siska, Verellen J, Gosselink R, Vanlandewijck Y C
Faculty of Physical Education and Physiotherapy, Department of Rehabilitation Sciences, KU Leuven, Tervuursevest 101, 3001, Leuven, Belgium.
Eur J Appl Physiol. 2003 Nov;90(5-6):581-7. doi: 10.1007/s00421-003-0910-7. Epub 2003 Aug 16.
Isocapnic hyperpnoea has been shown to reliably produce fatigue of the diaphragm. The aim of the present study was to investigate whether incremental isocapnic hyperpnoea (IH(incr)) impairs the arm exercise performance and alters the breathing pattern during subsequent maximal incremental arm cranking. Nine healthy volunteers performed an arm cranking test with prior IH(incr) (AC(IH)) and without prior IH(incr) (AC(control)). Minute ventilation ( V(E)), tidal volume ( V(T)), breathing frequency ( f(b)), O(2) uptake ( VO(2)), CO(2) elimination ( VCO(2)), respiratory exchange ratio (RER) and end-tidal partial pressure of CO(2) ( P(ET)CO(2)) were measured at three different time intervals ( t(1): the average of the 3.30th min to the 6.30th min, t(2): 1 min before the end, t(3): peak value) and expressed as mean (SD). V(T) at t(1) and at t(3) was significantly ( P<0.05) lower during AC(IH) [AC(control): t(1): 1.3 (0.5) l, t(p): 1.9 (0.3) l; AC(IH): t(1): 1.1 (0.3) l, t(p): 1.6 (0.3) l]. f(b) at t(1) and t(2) was significantly ( P<0.05) higher during AC(IH) [AC(control): t(1): 23 (4) breaths min(-1), t(2): 42 (14) breaths min(-1); AC(IH): t(1): 27 (5) breaths min(-1), t(2): 48 (14) breaths min(-1)]. The maximal voluntary ventilation (MVV), measured before and immediately after the IH(incr), demonstrated a small but significant decrease from 157 (15) l min(-1) to 150 (14) l min(-1) ( P<0.05) after the IH(incr). In conclusion, rapid shallow breathing occurred during maximal arm cranking exercise after IH(incr). The alteration was irrespective of the workload and had already occurred at the start of exercise.
等碳酸过度通气已被证明能可靠地导致膈肌疲劳。本研究的目的是调查递增等碳酸过度通气（IH(incr)）是否会损害手臂运动表现，并在随后的最大递增手臂曲柄运动期间改变呼吸模式。九名健康志愿者进行了一次手臂曲柄测试，一次是在有IH(incr)之前（AC(IH)），另一次是在没有IH(incr)之前（AC(对照)）。在三个不同的时间间隔（t(1)：第3.30分钟至第6.30分钟的平均值，t(2)：结束前1分钟，t(3)：峰值）测量分钟通气量（V(E)）、潮气量（V(T)）、呼吸频率（f(b)）、氧气摄取量（VO(2)）、二氧化碳排出量（VCO(2)）、呼吸交换率（RER）和呼气末二氧化碳分压（P(ET)CO(2)），并表示为平均值（标准差）。在AC(IH)期间，t(1)和t(3)时的V(T)显著（P<0.05）降低[AC(对照)：t(1)：1.3（0.5）升，t(3)：1.9（0.3）升；AC(IH)：t(1)：1.1（0.3）升，t(3)：1.6（0.3）升]。在AC(IH)期间，t(1)和t(2)时的f(b)显著（P<0.05）升高[AC(对照)：t(1)：23（4）次呼吸/分钟，t(2)：42（14）次呼吸/分钟；AC(IH)：t(1)：27（5）次呼吸/分钟，t(2)：48（14）次呼吸/分钟]。在IH(incr)之前和之后立即测量的最大自主通气量（MVV）显示，在IH(incr)之后从157（15）升/分钟小幅但显著下降至150（14）升/分钟（P<0.05）。总之，在IH(incr)之后的最大手臂曲柄运动期间出现了快速浅呼吸。这种改变与工作量无关，并且在运动开始时就已经发生。
