Kaito K, Otsubo H, Usui N, Kobayashi M
Division of Hematology and Oncology, Department of Internal Medicine, The Jikei University School of Medicine, 3-19-18 Nishi Shinbashi, Minato-ku, 105-8471 Tokyo, Japan.
Ann Hematol. 2004 Jan;83(1):55-7. doi: 10.1007/s00277-003-0745-7. Epub 2003 Aug 16.
A 45-year-old man was referred to our hospital because of polycythemia. A physical examination revealed a large tumor in his scrotum enlarged to the size of 13 x 10 cm. A laboratory examination revealed severe erythrocytosis with a red blood cell count of 6,820 x 10(9)/L, a hemoglobin concentration of 21.2 g/dL, and a hematocrit of 59.8%. The total red cell volume was increased. A right radical orchidectomy was done with minimum bleeding, and he was diagnosed as having pure seminoma. After the operation, polycythemia improved spontaneously. Polycythemia is a rare complication of seminoma and only two cases have been reported previously. The precise mechanism of polycythemia in our patient could not be clearly evaluated, but clinical course did indicate a close relationship between two distinct disorders.
一名45岁男性因红细胞增多症转诊至我院。体格检查发现其阴囊内有一个巨大肿瘤，大小为13×10厘米。实验室检查显示严重红细胞增多，红细胞计数为6820×10⁹/L，血红蛋白浓度为21.2 g/dL，血细胞比容为59.8%。总红细胞体积增加。行右侧根治性睾丸切除术，出血极少，术后诊断为纯精原细胞瘤。术后红细胞增多症自发改善。红细胞增多症是精原细胞瘤的一种罕见并发症，此前仅报道过两例。该患者红细胞增多症的确切机制尚无法明确评估，但临床过程确实表明这两种不同疾病之间存在密切关系。
