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[病例报告:睾丸纯精原细胞瘤术后2年转移至肋骨]

[A case report: testicular pure seminoma metastasized to costal bone after 2 years post-operatively].

作者信息

Watanabe Miho, Kamai Takao, Masuda Akinori, Huruya Nobutaka, Yonezawa Tomoko, Niakanishi Kimihiro, Kambara Tsunehito, Tsujii Toshihiko, Yoshida Ken-Ichiro

机构信息

Department of Urology, Dokkyo University School of Medicine.

出版信息

Hinyokika Kiyo. 2004 Jul;50(7):505-9.

Abstract

A 32-year-old man underwent orchiectomy for his right testicular tumor (pure seminoma, pT1, stage A(I)). Pelvic and para-aortic lymph nodes were irradiated with 18 Gy as adjuvant therapy. Two years later, he developed low back pain. Computed tomography, magnetic resonance imaging and bone scans showed an enhanced mass at the 10th left costa. Aspiration cytology showed seminoma. After administration of chemotherapy with bleomycin, etoposide and cisplatinum, following high dose chemotherapy with peripheral blood stem cell transplantation, the costal lesion was diminished and symptoms relieved. Then radical costectomy was performed. A histopathological study showed non-viable cells of seminoma. Post-operative progress was uneventful. Testicular pure seminoma with bone metastasis is rare, and to our knowledge, only 9 cases have been reported.

摘要

一名32岁男性因右侧睾丸肿瘤(纯精原细胞瘤,pT1,A(I)期)接受了睾丸切除术。盆腔和腹主动脉旁淋巴结接受了18 Gy的照射作为辅助治疗。两年后,他出现了腰痛。计算机断层扫描、磁共振成像和骨扫描显示左第10肋骨处有一强化肿块。穿刺细胞学检查显示为精原细胞瘤。在用博来霉素、依托泊苷和顺铂进行化疗,并进行外周血干细胞移植的大剂量化疗后,肋骨病变缩小,症状缓解。随后进行了根治性肋骨切除术。组织病理学研究显示精原细胞瘤的无活性细胞。术后恢复顺利。睾丸纯精原细胞瘤伴骨转移罕见,据我们所知,仅报道过9例。

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