Sobin Leslie H
Department of Hepatic and Gastrointestinal Pathology, Armed Forces Institute of Pathology, Washington, DC 20306, USA.
Semin Surg Oncol. 2003;21(1):19-22. doi: 10.1002/ssu.10017.
This article describes changes and clarifications in the 6th edition of TNM that concern site-independent rules, regarding such aspects as sentinel lymph node biopsy, methods to distinguish between micrometastasis and isolated tumor cells, classification of tumors undergoing treatment, tumor deposits in lymph drainage beds, the number of lymph nodes needed for pathologic classification, and classification of residual tumor. These changes mainly reflect advances in diagnosis and treatment, and modulate rather than change the basic rules of classification.
本文描述了《肿瘤学分期手册》（TNM）第6版中与部位独立规则相关的变化及说明，涉及前哨淋巴结活检、微转移与孤立肿瘤细胞的区分方法、正在接受治疗的肿瘤分类、淋巴引流床中的肿瘤沉积物、病理分类所需的淋巴结数量以及残留肿瘤的分类等方面。这些变化主要反映了诊断和治疗方面的进展，是对分类基本规则的调整而非改变。
