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2单位红细胞单采术后红细胞容积的恢复

Restoration of red blood cell volume following 2-unit red blood cell apheresis.

作者信息

Valeri C R, Ragno G, Srey R

机构信息

Naval Blood Research Laboratory, Boston University School of Medicine, Boston, MA 02118, USA.

出版信息

Vox Sang. 2003 Aug;85(2):85-7. doi: 10.1046/j.1423-0410.2003.00333.x.

DOI:10.1046/j.1423-0410.2003.00333.x
PMID:12925159
Abstract

BACKGROUND AND OBJECTIVES

Blood donors who weigh at least 130 lbs (59 kg) and have a haematocrit of at least 40 V per cent can donate 2 units of blood, from which a 360-ml volume of red blood cells (RBC) can be isolated. This study was carried out in seven healthy male blood donors to assess the restoration of the RBC volume 1 month following a 2-unit RBC apheresis procedure.

MATERIALS AND METHODS

RBC volumes were measured prior to donation and 4 weeks after the 2-unit RBC apheresis procedure without oral iron supplementation.

RESULTS

Four weeks after the removal of 2 units of RBC from the male donors not supplemented with oral iron, the RBC volume was restored to 92% of the precollection value. The 360-ml volume of RBC collected represented 12-19% of the donor's original RBC volume.

CONCLUSIONS

Male donors can safely donate 2 units of RBC and will restore a mean of 92% of their RBC volume within 1 month without iron supplementation.

摘要

背景与目的

体重至少130磅(59千克)且血细胞比容至少为40%的献血者可捐献2单位血液,从中可分离出360毫升的红细胞(RBC)。本研究对7名健康男性献血者进行,以评估在进行2单位红细胞单采程序1个月后红细胞体积的恢复情况。

材料与方法

在献血前以及进行2单位红细胞单采程序且未口服补铁4周后测量红细胞体积。

结果

在未口服补铁的男性献血者被采集2单位红细胞4周后,红细胞体积恢复至采集前值的92%。采集的360毫升红细胞体积占献血者原始红细胞体积的12% - 19%。

结论

男性献血者可安全捐献2单位红细胞,且在不补铁的情况下1个月内平均可恢复其红细胞体积的92%。

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