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[氚标记亮氨酸掺入小鼠神经元和神经胶质细胞的放射自显影研究]

[Autoradiographic study of the incorporation of tritiated leucine into mouse neurons and glial cells].

作者信息

Dadoune J P, Baudrimont M

出版信息

C R Seances Soc Biol Fil. 1975;169(4):851-5.

PMID:129252
Abstract

The renewal of labeled proteins in neuronal and glial cells was investigated by means of quantitative light microscope radioautography. Adult and young mice were sacrificed at long intervals after one tritiated leucine injection. Results shpwed the persistance of an increased quantity of label in the young glial cells. For both adult and young, the relative rate of labeled protein breakdown was higher in oligodendrocytes than in astrocytes.

摘要

通过定量光学显微镜放射自显影术研究了神经元和神经胶质细胞中标记蛋白质的更新情况。在注射一次氚标记的亮氨酸后,对成年和幼年小鼠进行长时间间隔处死。结果显示,幼年神经胶质细胞中标记物数量持续增加。对于成年和幼年小鼠,少突胶质细胞中标记蛋白质的相对分解速率高于星形胶质细胞。

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