Rosenthall L
Montreal General Hospital, McGill University, Canada.
Curr Opin Radiol. 1992;4(6):62-9.
The diagnosis of osteomyelitis in the presence of fracture and orthopedic appliances and in the diabetic foot can be a formidable challenge to radionuclide imaging. Radiophosphate is highly sensitive in detecting bone disease, but of low specificity; to improve specificity it must be complemented by 67Ga or radiolabeled leukocytes. These latter agents are not without limitations, and the search for new agents and novel imaging strategies continues. The relative roles of nuclear medicine and MR imaging are coming into focus, and a diagnostic algorithm based on the shortcomings of both methods is suggested.
在存在骨折、骨科器械以及糖尿病足的情况下，骨髓炎的诊断对放射性核素成像而言可能是一项艰巨的挑战。放射性磷酸盐在检测骨疾病方面高度敏感，但特异性较低；为提高特异性，必须用67镓或放射性标记白细胞进行补充。后一类试剂并非没有局限性，对新型试剂和新颖成像策略的探索仍在继续。核医学与磁共振成像的相对作用正受到关注，并提出了一种基于两种方法缺点的诊断算法。
