Liu Feng-Yuan, Shiau Yu-Chien, Kao Albert, Liang Ji-An, Yang Shih-Neng
Department of Nuclear Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan.
Anticancer Res. 2003 May-Jun;23(3C):2951-3.
The aim of this study was to evaluate the usefulness of the Tc-99m tetrofosmin (Tc-99m TF) scan to detect Non-Hodgkin's lymphoma (NHL). Before any therapy, 26 patients with NHL were included in this study to undergo Tc-99m TF scan. Whole body Tc-99m TF scan was performed 10 minutes after intravenous injection of 20 mCi Tc-99m TF. Tc-99m TF scan could detect NHL in 22 (84.6%) patients. However, there were no significant differences in the incidences of positive and negative Tc-99m TF scan results between female versus male patients, age > 40 years and < or = 40 years patients, stage I-II versus stage III-IV patients and patients with versus without B symptoms (p values > 0.05). Four (15.4%) infradiaphragmatic NHL had false-negative Tc-99m TF scan results. We concluded that the Tc-99m TF scan is a potential tool to detect supradiaphragmatic NHL.
本研究的目的是评估锝-99m替曲膦（Tc-99m TF）扫描检测非霍奇金淋巴瘤（NHL）的有效性。在进行任何治疗之前，本研究纳入了26例NHL患者进行Tc-99m TF扫描。静脉注射20毫居里Tc-99m TF后10分钟进行全身Tc-99m TF扫描。Tc-99m TF扫描能够在22例（84.6%）患者中检测到NHL。然而，女性与男性患者、年龄＞40岁与≤40岁患者、Ⅰ-Ⅱ期与Ⅲ-Ⅳ期患者以及有与无B症状的患者之间，Tc-99m TF扫描结果阳性与阴性的发生率无显著差异（p值＞0.05）。4例（15.4%）膈下NHL的Tc-99m TF扫描结果为假阴性。我们得出结论，Tc-99m TF扫描是检测膈上NHL的一种潜在工具。
