Popova T N
Medical State University, Saratov.
Vopr Onkol. 2003;49(3):363-6.
The data on 526 patients treated for primary multiple synchronous malignancies were evaluated. The total number of detected tumors was 1,069; concomitant pathology was identified in 377 out of 490 (76.9 +/- 1.9%). Removal of all synchronous tumors was considered radical--and palliative or symptomatic when, whatever the modality, two or at least one tumor was treated. Most of primary multiple synchronous tumors were removed radically (56.4 +/- 2.3%). The best results were obtained when combined therapy was used for early-stage tumors while surgical treatment of advanced cancer was complemented with radiochemotherapy. Radical treatment was contraindicated in 30.3 +/- 3.8% because of concomitant pathology.
对526例接受原发性多灶同步恶性肿瘤治疗的患者数据进行了评估。检测到的肿瘤总数为1069个；在490例患者中，有377例（76.9±1.9%）发现了合并病变。无论采用何种方式，当治疗两个或至少一个肿瘤时，所有同步肿瘤的切除被视为根治性——以及姑息性或对症性治疗。大多数原发性多灶同步肿瘤被根治性切除（56.4±2.3%）。当对早期肿瘤采用联合治疗，而对晚期癌症的手术治疗辅以放化疗时，可获得最佳结果。由于合并病变，30.3±3.8%的患者禁忌进行根治性治疗。
