Danielides V, Katotomichelakis M, Homsioglou E, Koukourakis M I, Giatromanolaki A, Sivridis E
Department of Otorhinolaryngology, Medical School, Democritus University of Thrace, Greece.
B-ENT. 2007;3(1):45-8.
Reports indicate that the incidence of multiple primary tumours in head and neck cancers is high. However, most of these tumours are either metachronous primary or secondary tumours of the same histopathological type. The development of a synchronous primary squamous cell skin cancer of the nose and an in-situ vocal cord carcinoma is something unusual. We present the case of a patient with a primary neoplasm along the lateral side of the nose up to the bone of the pyramid, including the skin of the inner side of the nose and an infiltration of the inferior nasal concha on the right side, together with a small synchronous primary lesion of the left vocal cord. To the best of our knowledge the case described is the first in the English medical literature and we discuss the complete management of synchronous head and neck malignancies, emphasising the importance of panendoscopy in the prevention of pitfalls in diagnosis and the therapeutic procedure.
报告表明，头颈癌中多原发性肿瘤的发生率很高。然而，这些肿瘤大多数是异时性原发性肿瘤或相同组织病理学类型的继发性肿瘤。鼻同步原发性鳞状细胞皮肤癌和原位声带癌的发生情况较为罕见。我们报告一例患者，其原发性肿瘤沿鼻外侧直至鼻锥体骨，包括鼻内侧皮肤及右侧下鼻甲浸润，同时左侧声带存在一个小的同步原发性病变。据我们所知，该病例是英文医学文献中的首例，我们讨论了同步性头颈恶性肿瘤的完整治疗，强调了全内镜检查在预防诊断和治疗过程中陷阱方面的重要性。
