Hamilton Steven J
US Geological Survey, Columbia Environmental Research Center, Field Research Station, 31247 436th Avenue, Yankton, SD 57078-6364, USA.
Ecotoxicol Environ Saf. 2003 Oct;56(2):201-10. doi: 10.1016/s0147-6513(02)00091-x.
A variety of guidelines have been proposed in recent years for linking selenium concentrations in the whole body of fish or in diet with adverse effects in fish. Diverging viewpoints seem to be forming separating groups supporting either the low-selenium guidelines proposed by the government and academic researchers or the high-selenium guidelines proposed by other researchers. Recently, an article was published that reviewed selected studies and recommended guidelines for selenium concentrations in the whole body of fish and in diet that were higher than those proposed by other researchers (approximately 4 microg/g in whole body and 3-4 microg/g in diet). That article also recommended separating guidelines for coldwater fish (6 microg/g in whole body and 11 microg/g in diet) and warmwater fish (9 microg/g in whole body and 10 microg/g in diet). The approaches, information, and guidelines presented in the article are reviewed and problems in their interpretation and conclusions are discussed. The majority of the selenium literature supports a whole-body threshold of 4 microg/g in fish and 3 microg/g in diet.
近年来，人们提出了各种指导方针，用于将鱼类全身或饮食中的硒浓度与鱼类的不良反应联系起来。不同的观点似乎正在形成不同的群体，一方支持政府和学术研究人员提出的低硒指导方针，另一方支持其他研究人员提出的高硒指导方针。最近，发表了一篇文章，该文章回顾了一些选定的研究，并推荐了鱼类全身和饮食中硒浓度的指导方针，这些指导方针高于其他研究人员提出的指导方针（全身约4微克/克，饮食中3 - 4微克/克）。该文章还推荐了冷水鱼（全身6微克/克，饮食中11微克/克）和温水鱼（全身9微克/克，饮食中10微克/克）的单独指导方针。本文对该文章中提出的方法、信息和指导方针进行了综述，并讨论了其解释和结论中存在的问题。大多数硒相关文献支持鱼类全身阈值为4微克/克，饮食中为3微克/克。
