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用于增强下食管括约肌的注射剂和容积形成剂。

Injectable and bulk-forming agents for enhancing the lower esophageal sphincter.

作者信息

Lehman Glen A

机构信息

Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

出版信息

Am J Med. 2003 Aug 18;115 Suppl 3A:188S-191S. doi: 10.1016/s0002-9343(03)00222-5.

DOI:10.1016/s0002-9343(03)00222-5
PMID:12928100
Abstract

Promising endoscopic therapies for gastroesophageal reflux disease (GERD), including suturing and stapling techniques and injections of inert implantable materials, are emerging in both clinical practice and clinical investigations. Suturing and stapling techniques have undergone rapid development in the past few years. However, there are some potential advantages to the use of implantation procedures. These procedures are likely to be the least expensive to perform and also appear to be the least technically demanding. The various procedures and equipment have yet to undergo head-to-head clinical evaluation. The utility of endoscopic therapies for GERD will become more apparent when adequate data are available from well-controlled clinical trials and procedural databases. Further refinement, development, and differentiation of various endoscopic techniques are anticipated.

摘要

治疗胃食管反流病(GERD)的有前景的内镜治疗方法正在临床实践和临床研究中不断涌现,包括缝合和吻合技术以及惰性可植入材料注射。在过去几年中,缝合和吻合技术发展迅速。然而,采用植入手术有一些潜在优势。这些手术实施起来可能成本最低,而且似乎对技术要求也最低。各种手术和设备尚未进行直接的临床评估。当从严格控制的临床试验和手术数据库中获得足够数据时,内镜治疗GERD的效用将更加明显。预计各种内镜技术将得到进一步完善、发展和分化。

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