Voloudaki A, Ergazakis N, Gourtsoyiannis N
Department of Radiology, University Hospital of Heraklion, 71110 Crete, Greece.
Eur Radiol. 2003 Sep;13(9):2226-9. doi: 10.1007/s00330-002-1687-5. Epub 2002 Oct 12.
Aspiration of barium sulfate occurs accidentally. Lung reaction is usually mild in the early phase due to inert character of the substance and long-term reactions or late toxicities are not expected. Little if any fibrotic response is speculated. We present a case with barium aspiration, studied by high-resolution computed tomography (HRCT) 1 year after the event, as late pulmonary sequelae studied by CT have not been described yet, to the best of our knowledge. The HRCT revealed thickened interlobular septa, subpleural lines, subpleural cysts, and centrilobular micronodules along with barium particles in a subpleural distribution. Those findings indicated that barium is capable of producing mild though silent clinically fibrosis.
硫酸钡误吸偶然发生。由于该物质的惰性，肺部反应在早期通常较轻，预计不会出现长期反应或晚期毒性。推测几乎不会有纤维化反应。据我们所知，尚未有关于CT研究的硫酸钡误吸晚期肺部后遗症的报道，我们在此呈现一例硫酸钡误吸病例，在误吸事件发生1年后进行了高分辨率计算机断层扫描（HRCT）检查。HRCT显示小叶间隔增厚、胸膜下线、胸膜下囊肿和小叶中心微结节，同时胸膜下分布有钡颗粒。这些发现表明钡能够产生轻度的、临床上无症状的纤维化。
