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结节病中的骨囊肿:其临床意义是什么?

Bone cysts in sarcoidosis: what is their clinical significance?

作者信息

Yanardağ Halil, Pamuk Omer Nuri

机构信息

Department of Lung Diseases, Cerrahpaşa Medical Faculty, University of Istanbul, Istanbul, Turkey.

出版信息

Rheumatol Int. 2004 Sep;24(5):294-6. doi: 10.1007/s00296-003-0370-8. Epub 2003 Aug 20.

DOI:10.1007/s00296-003-0370-8
PMID:12928974
Abstract

The incidence of bone cysts in sarcoidosis, a multisystemic disease, varies in different series, and these cysts are generally asymptomatic. We evaluated bone cysts in 516 sarcoidosis patients with available hand X-rays and in 200 patients with foot X-rays. Bone cysts were present in 21 cases (19 females, two males). The cysts were localized in phalanges of the hand in all cases, in feet in five cases, and in nasal bone in one. Six patients with bone cysts also had lupus pernio. Among those with cystic bone lesions, females were more frequent; extrapulmonary and skin involvement and lupus pernio were significantly more common. We diagnosed cystic bone lesions in 3.6% of our sarcoidosis patients and conclude that cysts were more frequent in females and in patients with lupus pernio.

摘要

结节病是一种多系统疾病,骨囊肿在其中的发生率在不同系列研究中有所差异,且这些囊肿通常无症状。我们对516例有手部X线片的结节病患者以及200例有足部X线片的患者进行了骨囊肿评估。骨囊肿出现在21例患者中(19例女性,2例男性)。所有病例中囊肿均位于手部指骨,5例位于足部,1例位于鼻骨。6例有骨囊肿的患者同时患有冻疮样狼疮。在有囊性骨病变的患者中,女性更为常见;肺外和皮肤受累以及冻疮样狼疮显著更为常见。我们在3.6%的结节病患者中诊断出囊性骨病变,并得出结论:囊肿在女性以及患有冻疮样狼疮的患者中更为常见。

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1
Bone cysts in sarcoidosis: what is their clinical significance?结节病中的骨囊肿:其临床意义是什么?
Rheumatol Int. 2004 Sep;24(5):294-6. doi: 10.1007/s00296-003-0370-8. Epub 2003 Aug 20.
2
Lupus pernio with multiple bone cysts in the fingers.冻疮样狼疮伴手指多发骨囊肿。
J Dermatol. 2010 Sep;37(9):812-4. doi: 10.1111/j.1346-8138.2010.00900.x.
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Extensive phalangeal cystic lesions: sarcoidosis limited to the hands and feet?广泛的指(趾)骨囊性病变:结节病是否局限于手足部位?
Arthritis Rheum. 1975 Mar-Apr;18(2):123-8. doi: 10.1002/art.1780180207.
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Lupus pernio: a clinico-radiological study of thirty-five cases.冻疮样狼疮:35例临床放射学研究
Br J Dermatol. 1985 Mar;112(3):315-22. doi: 10.1111/j.1365-2133.1985.tb04859.x.
5
[The bone manifestations in 94 cases of sarcoidosis].[94例结节病的骨骼表现]
An Med Interna. 1991 Oct;8(10):481-6.
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Radiological changes in hands and feet in disabled leprosy patients: a clinico-radiological correlation.残疾麻风病患者手足的放射学改变:临床与放射学相关性研究
Indian J Lepr. 1992 Jan-Mar;64(1):58-66.
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[Incidence of cystic bone alterations (ostitis cystoides multiplex Jüngling) in sarcoidosis].[结节病中囊性骨改变(Jüngling多发性囊性骨炎)的发病率]
Dtsch Med Wochenschr. 1970 Sep 18;95(38):1926-9. doi: 10.1055/s-0028-1108755.
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[Bone changes in sarcoidosis].[结节病中的骨骼改变]
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Sarcoidosis: An unusual presentation.结节病:一种不寻常的表现。
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[Primary cavern formation in acute sarcoidosis].[急性结节病中的原发性空洞形成]
Orv Hetil. 1982 Dec 12;123(50):3087-9.

引用本文的文献

1
Familial early onset sarcoidosis with bone cysts and erosions.伴有骨囊肿和骨侵蚀的家族性早发型结节病
Skeletal Radiol. 2007 Sep;36(9):891-3. doi: 10.1007/s00256-007-0315-5. Epub 2007 May 11.

本文引用的文献

1
Osseous sarcoidosis clinical, radiographic, and therapeutic observations.骨结节病的临床、影像学及治疗观察
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A study of sarcoidosis; based on a combined investigation of 160 cases including 30 autopsies from The Johns Hopkins Hospital and Massachusetts General Hospital.一项关于结节病的研究;基于对约翰霍普金斯医院和麻省总医院160例病例(包括30例尸检)的联合调查。
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结节病:免疫学、风湿性累及及治疗学
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Bone sarcoidosis.骨结节病
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Osseous disease in patients with pulmonary sarcoidosis and musculoskeletal symptoms.患有肺部结节病及肌肉骨骼症状患者的骨病
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Medicine (Baltimore). 1999 Mar;78(2):65-111. doi: 10.1097/00005792-199903000-00001.
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Sclerotic lesions of the cervical spine in sarcoidosis.
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Sarcoidosis and cancer revisited: a long-term follow-up study of 555 Danish sarcoidosis patients.结节病与癌症再探讨:对555名丹麦结节病患者的长期随访研究
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The nasal bones, an uncommon localization of sarcoidosis. Report of a new case.鼻骨是结节病的一种罕见发病部位。一例新病例报告。
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[Osteoarticular sarcoidosis].[骨关节结节病]
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