Ruan Aidong, Min Hang, Meng Ziqiang, Lü Zhenmei
College of Life Science, Zhejiang University, Hangzhou, China.
Inhal Toxicol. 2003 Sep;15(10):1053-8. doi: 10.1080/08958370390226558.
Sulfur dioxide (SO2) is a common but important air pollutant. Micronuclei (MN) in the polychromatic erythrocytes (PCE) of mouse bone marrow and the ratio between organ and body weight of treatment mouse were determined and analyzed in vivo in order to study injury of sulfur dioxide inhalation on organs and germ plasm of mouse as well as protective effect of seabuckthorn seed oil against this injury. It was showed that SO2 inhalation induced the change of the ratio between organ and body of mouse organs, such as liver, lung, kidney, and spleen, and a significant increase of number of MNPCE, while seabuckthorn seed oil offered a protection against such injury.
二氧化硫（SO₂）是一种常见但重要的空气污染物。为了研究吸入二氧化硫对小鼠器官和种质的损伤以及沙棘籽油对这种损伤的保护作用，在体内测定并分析了小鼠骨髓多染红细胞（PCE）中的微核（MN）以及处理小鼠的器官与体重之比。结果表明，吸入SO₂会导致小鼠肝脏、肺、肾和脾等器官的器官与体重之比发生变化，且微核多染红细胞数量显著增加，而沙棘籽油可对此损伤起到保护作用。
