Schräder P, Scharf H-P, Günther K-P, Puhl W, Porzsolt F
Orthopädische Universitätsklinik Mannheim, Germany.
Z Orthop Ihre Grenzgeb. 2003 Jul-Aug;141(4):386-90. doi: 10.1055/s-2003-41571.
The methods of evidence based medicine (EBM) are recommended to solve problems in day-to-day routine. Aim of this article is to demonstrate the practicability of this procedure for the diagnostic module.
Within a teaching session in our department 20 participants guided by an extern al EBM teacher validated the results of an article according to the EBM criteria concerning the module "diagnosis". We demonstrate what EBM can contribute to solve day-to-day clinical problems and discuss the six formal steps for the implementation of EBM into day-to-day practice. 1) To transform the clinical problem into an answerable 4-part question. 2) To answer this question based on your internal evidence. 3) To search for external evidence to answer this question. 4) To critically appraise the evidence found with respect to its validity, importance and applicability. 5) To integrate the appraised external evidence into your existing internal evidence in order to come to a new decision if the additional new external evidence is convincing. 6) To assess the benefit which was gained for the patient.
Statistical tests to evaluate the relevance and validity of the chosen article were performed. The following data were determined: sensitivity, specifity, pretest probability, posttest probability, likelihood ratio, positive predictive value, negative predictive value.
In conclusion we show that EBM can help to solve day-to-day clinical problems, because the structured analysis of concrete questions can lead to a validation of the literature.
推荐循证医学(EBM)方法用于解决日常临床问题。本文旨在证明该方法在诊断模块中的实用性。
在我们科室的一次教学活动中,20名参与者在一名外部循证医学教师的指导下,根据循证医学标准对一篇关于“诊断”模块的文章结果进行了验证。我们展示了循证医学在解决日常临床问题方面的作用,并讨论了将循证医学应用于日常实践的六个正式步骤。1)将临床问题转化为一个可回答的四部分问题。2)根据你自己的内部证据回答这个问题。3)寻找外部证据来回答这个问题。4)批判性地评估所发现证据的有效性、重要性和适用性。5)将评估后的外部证据与你现有的内部证据相结合,以便在额外的新外部证据令人信服时做出新的决策。6)评估为患者带来的益处。
对所选文章的相关性和有效性进行了统计检验。确定了以下数据:敏感性、特异性、验前概率、验后概率、似然比、阳性预测值、阴性预测值。
总之,我们表明循证医学有助于解决日常临床问题,因为对具体问题的结构化分析可以导致对文献的验证。