Coutouli-Argyropoulou Evdoxia, Tsitabani Maria, Petrantonakis Georgios, Terzis Aris, Raptopoulou Catherine
Department of Chemistry, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Org Biomol Chem. 2003 Apr 21;1(8):1382-8. doi: 10.1039/b300191a.
The Sonogashira coupling reaction of ethynylferrocene with adenine, uracil, tyrosine and steroid derivatives was studied; with the exception of tyrosine it was proved to be a good route for the attachment of ferrocene to these representative biomolecules. In addition the transformation of alkynyl uracil to furanopyrimidone derivatives was investigated and the formation of the furanopyrimidone ring was confirmed by an X-ray crystallographic analysis carried out on product 16.
