Josso N
Unité de Recherches sur l'Endocrinologie du Développement (INSERM), Montrouge, France.
Horm Res. 1992;38 Suppl 2:72-6. doi: 10.1159/000182602.
Anti-müllerian hormone (AMH) is a glycoprotein that is produced by immature Sertoli cells and is responsible for the regression of müllerian ducts in male fetuses. It is a useful marker of testicular function in children, when anorchia is suspected and in intersex states. In the persistent müllerian duct syndrome, both AMH-positive and AMH-negative forms have been reported. In three cases of the latter, a mutation of the AMH gene is thought to have been responsible for the condition.
