Al Shaikh H A, Bappal B, Nair R, Al Khusaiby S
Paediatric Endocrinology and Metabolic Unit, Royal Hospital, Sultanate of Oman.
J Trop Pediatr. 2003 Aug;49(4):245-7. doi: 10.1093/tropej/49.4.245.
A retrospective study was conducted on 45 children with congenital hypothyroidism (CH) to estimate the number of missed cases of CH among Omani children per year and compare the intellectual outcome of children diagnosed by neonatal screening (Group A) with those who were diagnosed clinically at a later age (Group B). Our results revealed 14 children in Group A, diagnosed at a mean age of 2.3 +/- 0.8 months and 31 children in Group B diagnosed at a mean age of 9.8 +/- 2.5 months. IQ assessment revealed that 67 per cent of the children in Group A had a normal IQ compared to only 15 per cent of those in Group B. The above results point to a great demand for a national screening programme in the Sultanate of Oman.
对45名先天性甲状腺功能减退症（CH）患儿进行了一项回顾性研究，以估算阿曼每年漏诊的CH患儿数量，并比较通过新生儿筛查确诊的患儿（A组）与较晚临床诊断的患儿（B组）的智力发育结果。我们的结果显示，A组有14名患儿，平均诊断年龄为2.3±0.8个月；B组有31名患儿，平均诊断年龄为9.8±2.5个月。智商评估显示，A组67%的患儿智商正常，而B组只有15%的患儿智商正常。上述结果表明阿曼苏丹国对全国性筛查项目有很大需求。
