Nishimura N, Kato S, Ishikawa H, Takano T
Department of Microbiology, Keio University School of Medicine, Tokyo, Japan.
Intervirology. 1992;34(2):112-6. doi: 10.1159/000150270.
Mouse monoclonal antibodies were generated for three 20- to 23-mer synthetic peptides whose amino acid sequences were highly conserved in the pol or env regions of 14 mammalian and two avian retroviruses. By Western-blot analysis, these antibodies recognised the epitopes in major and minor pol or env proteins of six mammalian type-C and -D retroviruses. One of the anti-env monoclonal antibodies was found to recognise all the env transmembrane proteins of six mammalian retroviruses examined.
