Lawrence D, Bellah J R, Diaz R
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610-0126.
J Am Vet Med Assoc. 1992 Dec 1;201(11):1750-3.
Serum bile acid (SBA) values were obtained in 20 dogs, 2.5 to 60 months (mean, 18.6 months) after surgery for occlusion of a congenital portosystemic shunt. The SBA values obtained after food was withheld were significantly (P < 0.005) reduced at follow-up, compared with preoperative values. In 85% of the dogs (17/20), response to surgery was graded by the owners as excellent or good, although most dogs had abnormal SBA values at follow-up. Significant difference in clinical results or follow-up SBA values was not found in dogs that had complete or partial occlusion of the shunting vessel. Correlation between clinical results and SBA values also was not detected. Dogs that were > 2 years old at the time of diagnosis and surgery had a significantly (P = 0.012) poorer clinical result than that of dogs < 1 year old.
在20只犬进行先天性门体分流闭塞手术后2.5至60个月(平均18.6个月)测定血清胆汁酸(SBA)值。与术前值相比,禁食后获得的SBA值在随访时显著降低(P < 0.005)。85%的犬(17/20)主人将手术反应评为优秀或良好,尽管大多数犬在随访时SBA值异常。在分流血管完全或部分闭塞的犬中,未发现临床结果或随访SBA值有显著差异。也未检测到临床结果与SBA值之间的相关性。诊断和手术时年龄>2岁的犬临床结果明显(P = 0.012)比<1岁的犬差。