针对镰状细胞病患儿血管阻塞性疼痛危象的整体治疗方法。

A holistic approach to vaso-occlusive pain crisis in children with sickle cell disease.

作者信息

Houser B, Plawecki H M, Carr J, Smith M A, Plawecki J A

出版信息

J Holist Nurs. 1992 Mar;10(1):62-75. doi: 10.1177/089801019201000107.

DOI:10.1177/089801019201000107

Abstract

A significant number of children with sickle cell disease suffer from episodes of acute recurrent vaso-occlusive pain crisis. Unfortunately, very limited published information is available about specific pain management practices used for these patients. There is even less information available on the use of an interdisciplinary approach for management of sickle cell crisis pain. The purpose of this article is to review the genetic cellular pathophysiology, the sickling process, vaso-occlusive crisis, and management of pain associated with sickle cell disease in children. The article further examines an interdisciplinary approach for the management of vaso-occlusive pain crisis.

摘要

大量镰状细胞病患儿遭受急性复发性血管阻塞性疼痛危机发作之苦。不幸的是，关于用于这些患者的具体疼痛管理实践，公开信息非常有限。关于采用跨学科方法管理镰状细胞危机疼痛的信息更是少之又少。本文的目的是综述儿童镰状细胞病的遗传细胞病理生理学、镰变过程、血管阻塞性危机以及与之相关的疼痛管理。本文还进一步探讨了管理血管阻塞性疼痛危机的跨学科方法。