Chiang Yi-Ming, Kuo Yueh-Hsiung, Oota Shyuzo, Fukuyama Yoshiyasu
Department of Chemistry, National Taiwan University, Taipei, Taiwan, Republic of China.
J Nat Prod. 2003 Aug;66(8):1070-3. doi: 10.1021/np030065q.
Two new xanthone derivatives, garcinianones A (1) and B (2), two new benzophenone derivatives, 4,6,4'-trihydroxy-2,3'-dimethoxy-3-prenylbenzophenone (3) and 4,6,3',4'-tetrahydroxy-2-methoxybenzophenone (4), and a new inseparable mixture of (1E,22Z)-1,22-diferuloyloxydocosane and (1E,24Z)-1,24-diferuloyloxyteracosane (5), together with the previously known 3,8-dihydroxy-2,4,6-trimethoxyxanthone, 6,3'-dihydroxy-2,4-dimethoxybenzophenone, maclurin (6), 2,4,6,3'-tetrahydroxybenzophenone (7), and naringenin, were isolated from the stems of Garcinia multiflora. The structures of 1-5 were elucidated by extensive analysis of their spectral data. Compounds were evaluated in the brine shrimp lethality test and in the DPPH antioxidant assay.
从多花山竹子的茎中分离出两种新的氧杂蒽酮衍生物，藤黄氧杂蒽酮A（1）和B（2），两种新的二苯甲酮衍生物，4,6,4'-三羟基-2,3'-二甲氧基-3-异戊烯基二苯甲酮（3）和4,6,3',4'-四羟基-2-甲氧基二苯甲酮（4），以及一种新的不可分离的（1E,22Z）-1,22-二阿魏酰氧基二十二烷和（1E,24Z）-1,24-二阿魏酰氧基二十四烷混合物（5），同时还分离出了先前已知的3,8-二羟基-2,4,6-三甲氧基氧杂蒽酮、6,3'-二羟基-2,4-二甲氧基二苯甲酮、桑色素（6）、2,4,6,3'-四羟基二苯甲酮（7）和柚皮素。通过对其光谱数据的广泛分析阐明了1-5的结构。对化合物进行了卤虫致死试验和DPPH抗氧化测定。
