草药中富含黄烷酮的化学和生物学研究

Tianjin State Key Laboratory of Modern Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China.

Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshan Road, Nankai District, Tianjin 300193, China.

Molecules. 2017 Oct 11;22(10):1698. doi: 10.3390/molecules22101698.

Xanthones, as some of the most active components and widely distributed in various herb medicines, have drawn more and more attention in recent years. So far, 168 species of herbal plants belong to 58 genera, 24 families have been reported to contain xanthones. Among them, , , , , , and genera are plant resources with great development prospect. This paper summarizes the plant resources, bioactivity and the structure-activity relationships (SARs) of xanthones from references published over the last few decades, which may be useful for new drug research and development on xanthones.

近年来，由于其作为最活跃的成分之一广泛分布于各种草药中，因此二氢黄酮类化合物引起了越来越多的关注。到目前为止，已经有 168 种草药植物属于 58 属 24 科被报道含有二氢黄酮类化合物。其中，、、、、、和属是具有巨大发展前景的植物资源。本文综述了近几十年来文献报道的二氢黄酮类化合物的植物资源、生物活性和构效关系（SARs），这可能对二氢黄酮类化合物的新药研究与开发有用。