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胸主动脉覆膜支架移植物的中期结果:并发症与成像技术

Midterm outcomes of thoracic aortic stent-grafts: complications and imaging techniques.

作者信息

Chabbert Valérie, Otal Philippe, Bouchard Louis, Soula Philippe, Van Tuan Tran, Kos Xavier, Meites Geneviève, Claude Conil, Joffre Francis, Rousseau Hervé

机构信息

Department of Radiology, University of Rangueil, Toulouse, France.

出版信息

J Endovasc Ther. 2003 Jun;10(3):494-504. doi: 10.1177/152660280301000314.

Abstract

PURPOSE

To evaluate the midterm outcomes of thoracic aortic stent-grafting and the performance of computed tomographic angiography (CTA), radiography, and magnetic resonance angiography (MRA) in endograft surveillance.

METHODS

Forty-seven patients with traumatic thoracic aortic ruptures (n=16), aneurysms (n=14), false aneurysms (n=3), penetrating ulcers (n=3), and dissections (n=11) treated with stent-grafts were monitored in follow-up using chest radiography and CTA in all patients and MRA in 23 patients. Two perpendicular maximal aortic diameters, the sum of these diameters, and the elliptical cross-sectional area were determined and compared to baseline for the entire group and in subgroup analyses according to lesion type. CTA, MRA, and radiography were compared for their ability to detect endoleak, monitor stent-graft configuration, and measure aortic diameters.

RESULTS

The mortality rate was 8.5%. Severe complications were observed in 14.8% (6% neurological complications); 12 (25.5%) patients had primary endoleaks. Over a mean 11-month follow-up (range 0.25-46 months), the aortic diameters decreased for all patients without endoleak (p<0.001). In the diameter/area subgroup analyses, only the traumatic rupture cohort demonstrated significant decreases in all 4 measurements. CTA and MRA measurements correlated well, but chest radiography was superior to both for visualizing stent-graft shape. In terms of endoleak detection, MRA missed only 1 (12.5%) endoleak (type II) seen on CTA; there were no false positive results with MRA.

CONCLUSIONS

Morbidity and mortality observed after thoracic stent-grafting are acceptable. Radiography is better for monitoring stent-graft conformation, while CTA provides the best overall morphological information. The performance of MRA in endoleak detection is encouraging.

摘要

目的

评估胸主动脉支架植入术的中期疗效以及计算机断层血管造影(CTA)、X线摄影和磁共振血管造影(MRA)在腔内移植物监测中的表现。

方法

对47例接受支架植入术治疗的创伤性胸主动脉破裂(n = 16)、动脉瘤(n = 14)、假性动脉瘤(n = 3)、穿透性溃疡(n = 3)和夹层(n = 11)患者进行随访,所有患者均采用胸部X线摄影和CTA,23例患者采用MRA。测定两个相互垂直的主动脉最大直径、这些直径之和以及椭圆截面积,并与整个组的基线进行比较,并根据病变类型进行亚组分析。比较CTA、MRA和X线摄影检测内漏、监测支架移植物形态和测量主动脉直径的能力。

结果

死亡率为8.5%。观察到严重并发症的发生率为14.8%(6%为神经系统并发症);12例(25.5%)患者发生原发性内漏。在平均11个月的随访期内(范围0.25 - 46个月),所有无内漏患者的主动脉直径均减小(p < 0.001)。在直径/面积亚组分析中,只有创伤性破裂队列的所有4项测量值均有显著下降。CTA和MRA测量结果相关性良好,但胸部X线摄影在显示支架移植物形状方面优于两者。在检测内漏方面,MRA仅漏诊了1例(12.5%)CTA上显示的内漏(II型);MRA没有假阳性结果。

结论

胸主动脉支架植入术后观察到的发病率和死亡率是可以接受的。X线摄影在监测支架移植物形态方面更好,而CTA提供了最佳的整体形态学信息。MRA在检测内漏方面的表现令人鼓舞。

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