Shimizu S, Yasui C, Yasukawa K, Nakamura H, Shimizu H, Tsuchiya K
Department of Dermatology, Sapporo City General Hospital, North 11, West 13, Chuo-Ku, Sapporo 060-8604, Japan.
Br J Dermatol. 2003 Aug;149(2):400-4. doi: 10.1046/j.1365-2133.2003.05466.x.
While beta 2-microglobulin amyloidosis occurring in patients undergoing long-term dialysis is frequently associated with joint involvement, skin lesions have rarely been encountered. We report a 57-year-old man with extensive subcutaneous amyloid deposition forming large nodules on the buttocks; the patient had been on maintenance dialysis for 28 years. Although this condition is rare, a review of the literature indicates that the majority of such lesions occur around the buttock region.
虽然长期透析患者发生的β2-微球蛋白淀粉样变性常与关节受累有关，但皮肤病变很少见。我们报告一名57岁男性，有广泛的皮下淀粉样沉积，在臀部形成大结节；该患者已接受维持性透析28年。尽管这种情况罕见，但文献回顾表明，大多数此类病变发生在臀部区域周围。
