Fernández-Alonso J, Rios-Camacho C, Valenzuela-Castaño A, Rocha-Castilla J L
Department of Pathology, Hospital Universitario Virgen del Rocio, Sevilla, Spain.
J Clin Pathol. 1993 Aug;46(8):771-2. doi: 10.1136/jcp.46.8.771.
A 52 year old man who had been receiving haemodialysis for 13 years, with a history of renal tuberculosis, right ischial tuberculous osteomyelitis, and dialysis arthropathy, developed a soft tissue tumour in his left buttock. Histological analysis, immunohistological staining, and electron microscopic examination of the surgically removed tumour showed massive deposits of beta 2-microglobulin (beta 2-M) amyloid. This case shows the expanding clinical spectrum of this type of amyloidosis, and it is suggested that amyloid infiltration should be considered in the differential diagnosis of gluteal tumours in these patients.
一名52岁男性，已接受血液透析13年，有肾结核、右坐骨结核性骨髓炎和透析性关节病病史，其左臀部出现软组织肿瘤。对手术切除的肿瘤进行组织学分析、免疫组织化学染色和电子显微镜检查显示有大量β2-微球蛋白（β2-M）淀粉样蛋白沉积。该病例显示了这类淀粉样变性病不断扩大的临床谱，提示在这些患者臀部肿瘤的鉴别诊断中应考虑淀粉样蛋白浸润。
