Backonja Misha-Miroslav
Departments of Neurology, Anesthesiology, and Rehabilitation Medicine, University of Wisconsin Medical School, University of Wisconsin, Madison.
Anesth Analg. 2003 Sep;97(3):785-790. doi: 10.1213/01.ANE.0000062826.70846.8D.
Clinical research and practice have suffered because of lack of specificity when clinical diagnoses of pain are made. Distinction between neuropathic and inflammatory pain mechanisms is suggested, as well as the distinction between neuropathic pain from hypersensitivity pain disorders, previously termed neuropathic pain due to neurological dysfunction. Neuropathic pain is in this case defined as pain occurring in the ara of body affected by neurological disease or injury. This type of pain manifests not only with positive sensory phenomena such as pain, dysesthesia, and different types of hyperalgesia, but also with negative sensory phenomena and negative and positive motor and autonomic symptoms and signs.
由于在进行疼痛的临床诊断时缺乏特异性，临床研究和实践受到了影响。有人建议区分神经性疼痛和炎症性疼痛机制，以及区分来自超敏性疼痛障碍的神经性疼痛（以前称为神经功能障碍性神经性疼痛）。在这种情况下，神经性疼痛被定义为发生在受神经疾病或损伤影响的身体区域的疼痛。这种类型的疼痛不仅表现为疼痛、感觉异常和不同类型的痛觉过敏等阳性感觉现象，还表现为阴性感觉现象以及阴性和阳性运动及自主神经症状和体征。
