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经皮射频消融治疗肺部恶性肿瘤:与近距离放射治疗联合应用

Percutaneous radiofrequency ablation of pulmonary malignancies: combined treatment with brachytherapy.

作者信息

Jain Sapna K, Dupuy Damian E, Cardarelli Gene A, Zheng Zhen, DiPetrillo Thomas A

机构信息

Department of Diagnostic Imaging, Rhode Island Hospital, Brown Medical School, 593 Eddy St., Providence, RI 02903, USA.

出版信息

AJR Am J Roentgenol. 2003 Sep;181(3):711-5. doi: 10.2214/ajr.181.3.1810711.

DOI:10.2214/ajr.181.3.1810711
PMID:12933465
Abstract

OBJECTIVE

The purpose of this article is to report the clinical experience and technical feasibility of percutaneous radiofrequency ablation in conjunction with brachytherapy, a novel approach in the treatment of lung neoplasms. Data from three patients with lung malignancies illustrate the expanding therapeutic indications of this minimally invasive intervention.

CONCLUSION

Percutaneous radiofrequency ablation in conjunction with brachytherapy is a promising minimally invasive combination modality. It may be a treatment option for patients with primary, recurrent, or metastatic malignancies of the lung that are not amenable to surgery or further external beam radiation therapy.

摘要

目的

本文旨在报告经皮射频消融联合近距离放射治疗在肺癌治疗中的临床经验和技术可行性,这是一种治疗肺部肿瘤的新方法。三位肺癌患者的数据说明了这种微创干预不断扩大的治疗适应症。

结论

经皮射频消融联合近距离放射治疗是一种有前景的微创联合治疗方式。对于无法进行手术或进一步外照射放疗的原发性、复发性或转移性肺癌患者,它可能是一种治疗选择。

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Combination therapy involving radiofrequency ablation and targeted chemotherapy with bevacizumab plus paclitaxel and cisplatin in a rabbit VX2 lung tumor model.
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