采用气相色谱/质谱法测定人玻璃体液中的吗啡，并与放射免疫分析法进行比较。

Morphine determination by gas chromatography/mass spectroscopy in human vitreous humor and comparison with radioimmunoassay.

作者信息

Bermejo A M, Ramos I, Fernández P, López-Rivadulla M, Cruz A, Chiarotti M, Fucci N, Marsilli R

机构信息

Institute of Legal Medicine, Faculty of Medicine, University of Santiago de Compostela, Spain.

出版信息

J Anal Toxicol. 1992 Nov-Dec;16(6):372-4. doi: 10.1093/jat/16.6.372.

DOI:10.1093/jat/16.6.372

PMID:1293404

Abstract

A gas chromatographic-mass spectroscopic method (GC/MS) for morphine determination in human vitreous humor was developed. Reversed-phase solid-liquid extraction gave better sample purification compared with liquid-liquid or normal-phase solid-liquid extractions. In 10 real cases of death by heroin overdose, the correlation between the results obtained by GC/MS and by radioimmunoassay (RIA) was studied.

摘要

建立了一种气相色谱 - 质谱法（GC/MS）用于测定人玻璃体液中的吗啡。与液 - 液萃取或正相固 - 液萃取相比，反相固 - 液萃取能实现更好的样品净化。在10例海洛因过量致死的实际案例中，研究了GC/MS法和放射免疫分析法（RIA）所得结果之间的相关性。