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[鼻型结外NK/T细胞淋巴瘤]

[Extranodal NK/T cell lymphoma of the nasal type].

作者信息

Kurpis María, Diller Ana B, Calafat Patricia, Ruiz Lascano Alejandro

机构信息

Laboratorio de Patología, Servicio de Dermatología Hospital Privado Centro Médico de Córdoba.

出版信息

Rev Fac Cien Med Univ Nac Cordoba. 2002;59(1):117-20.

Abstract

The vast majority of lymphoma occurring in the testis are diffuse large B-cell Lymphoma. We report on a case of natural killer/T cell lymphoma in a forty four year old male, with bilateral testicular and cutaneous involvement with a highly aggressive course. The tumor cells were positive for both CD56 and Epstein Barr Virus, encoded EBER molecules, and showed focal angiocentric growth thus fullfilling the criteria for NK/T cell lymphoma of nasal type. Dermatopathologists and uropathologists should be aware of this rare entity which may only be diagnosed after extensive inmunohistochemical studies.

摘要

发生于睾丸的淋巴瘤绝大多数是弥漫性大B细胞淋巴瘤。我们报告一例44岁男性自然杀伤/T细胞淋巴瘤,双侧睾丸及皮肤受累,病程高度侵袭性。肿瘤细胞CD56和爱泼斯坦-巴尔病毒编码的EBER分子均呈阳性,并显示局灶性血管中心性生长,因此符合鼻型NK/T细胞淋巴瘤的标准。皮肤病理学家和泌尿病理学家应了解这种罕见的实体,其可能仅在广泛的免疫组织化学研究后才能诊断。

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