Kurpis María, Diller Ana B, Calafat Patricia, Ruiz Lascano Alejandro
Laboratorio de Patología, Servicio de Dermatología Hospital Privado Centro Médico de Córdoba.
Rev Fac Cien Med Univ Nac Cordoba. 2002;59(1):117-20.
The vast majority of lymphoma occurring in the testis are diffuse large B-cell Lymphoma. We report on a case of natural killer/T cell lymphoma in a forty four year old male, with bilateral testicular and cutaneous involvement with a highly aggressive course. The tumor cells were positive for both CD56 and Epstein Barr Virus, encoded EBER molecules, and showed focal angiocentric growth thus fullfilling the criteria for NK/T cell lymphoma of nasal type. Dermatopathologists and uropathologists should be aware of this rare entity which may only be diagnosed after extensive inmunohistochemical studies.
发生于睾丸的淋巴瘤绝大多数是弥漫性大B细胞淋巴瘤。我们报告一例44岁男性自然杀伤/T细胞淋巴瘤，双侧睾丸及皮肤受累，病程高度侵袭性。肿瘤细胞CD56和爱泼斯坦-巴尔病毒编码的EBER分子均呈阳性，并显示局灶性血管中心性生长，因此符合鼻型NK/T细胞淋巴瘤的标准。皮肤病理学家和泌尿病理学家应了解这种罕见的实体，其可能仅在广泛的免疫组织化学研究后才能诊断。
