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胃癌的个体化治疗

Individualizing therapy in gastric cancer.

作者信息

Sendler Andreas, Siewert J Rüdiger

机构信息

Chirurgische Klinik und Poliklinik, Klinikum rechts der Isar, München, Germany.

出版信息

Expert Rev Anticancer Ther. 2003 Aug;3(4):457-70. doi: 10.1586/14737140.3.4.457.

DOI:10.1586/14737140.3.4.457
PMID:12934658
Abstract

Although its incidence in developed countries has declined, gastric cancer remains one of the most common human malignancies. In western countries a shift from distal to proximal tumors has been noted during the past 15 years. Today, surgery is no longer the only treatment modality of gastric cancer, with the help of modern and sophisticated staging procedures it becomes increasingly possible to individually tailor therapy. Operative morbidity and mortality has markedly decreased. The importance of surgical expertise for short- as well as long-term outcome is emphasized. The knowledge of adequate surgery together with the use of combined modalities opens the door to the amelioration of the still dismal prognosis for patients with gastric cancer. This paper reviews the modern approach to gastric cancer using an individualized treatment concept.

摘要

尽管在发达国家胃癌的发病率有所下降,但它仍然是人类最常见的恶性肿瘤之一。在西方国家,过去15年中已注意到肿瘤有从远端向近端转移的趋势。如今,手术不再是胃癌的唯一治疗方式,借助现代精密的分期程序,越来越有可能针对个体制定治疗方案。手术的发病率和死亡率已显著降低。强调了手术专业知识对短期和长期治疗效果的重要性。充分的手术知识以及联合治疗方法的应用为改善胃癌患者仍然不佳的预后打开了大门。本文使用个体化治疗理念回顾了胃癌的现代治疗方法。

相似文献

1
Individualizing therapy in gastric cancer.胃癌的个体化治疗
Expert Rev Anticancer Ther. 2003 Aug;3(4):457-70. doi: 10.1586/14737140.3.4.457.
2
Gastric cancer: diagnosis and treatment options.胃癌:诊断与治疗选择
Am Fam Physician. 2004 Mar 1;69(5):1133-40.
3
Gastric cancer. Radiologic staging.胃癌。放射学分期。
Radiol Clin North Am. 1997 Mar;35(2):331-49.
4
The Italian Research Group for Gastric Cancer (GIRCG) guidelines for gastric cancer staging and treatment: 2015.意大利胃癌研究小组(GIRCG)胃癌分期与治疗指南:2015年版
Gastric Cancer. 2017 Jan;20(1):20-30. doi: 10.1007/s10120-016-0615-3. Epub 2016 Jun 2.
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Individualized surgical strategies for cancer of the esophagogastric junction.食管胃交界部癌的个体化手术策略
Ann Chir Gynaecol. 2000;89(3):191-8.
6
[Utilization of multimodal therapy concepts in stomach carcinoma in Germany].[德国胃癌多模式治疗理念的应用]
Zentralbl Chir. 2000;125(4):341-7.
7
New concepts of staging in gastrointestinal tumors as a basis of diagnosis and multimodal therapy.
Onkologie. 2004 Feb;27(1):23-30. doi: 10.1159/000075603.
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Cancer of the esophagus and gastric cardia: recent advances.食管癌和贲门癌:最新进展
Dis Esophagus. 2004;17(1):10-26. doi: 10.1111/j.1442-2050.2004.00371.x.
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[Influence of laparoscopic staging on therapy of stomach carcinoma].[腹腔镜分期对胃癌治疗的影响]
Chirurg. 2002 Apr;73(4):306-11. doi: 10.1007/s00104-002-0458-9.
10
Morbidity, mortality, and pathological response in patients with gastric cancer preoperatively treated with chemotherapy or chemoradiotherapy.胃癌患者术前接受化疗或放化疗的发病率、死亡率和病理反应。
J Surg Oncol. 2011 Aug 1;104(2):124-9. doi: 10.1002/jso.21947. Epub 2011 Apr 20.

引用本文的文献

1
[Tumors of the upper gastro-intestinal tract].[上消化道肿瘤]
Chirurg. 2010 Feb;81(2):103-6; 108-10. doi: 10.1007/s00104-009-1813-x.