Leskoviku S, Lasku A, Marku N, Rada F, Dibra A
Central Biochemical Laboratory, Hospital No. 1, Tirana, Albania.
Panminerva Med. 1992 Oct-Dec;34(4):168-71.
In our work we have studied the value of the determination of serum CEA in patients with colorectal cancer. We have studied 56 patients with colorectal cancer aged 40 +/- 16 years of both sexes, 26 of whom have metastasis and 30 not. The positivity of serum CEA in the patients with colorectal cancer was 66% (37/56) in the patients without metastasis 53% (16/30) and in the patients with metastasis 80.7%. (21/26). The referent values of serum CEA were significantly lower than the values of serum CEA in the patients with colorectal cancer with and without metastasis (p1 < 0.001). Also we noticed that the values of serum CEA of the patients with colorectal cancer with metastasis were considerably higher than those without metastasis (p2 < 0.001). Analysing the values of serum CEA in the patients with colorectal cancer we noticed that all the patients of our work that had serum CEA value 20 ng/ml had metastasis. Relying on our data we conclude that the determination of serum CEA in the patients with colorectal cancer is very useful for the diagnosis and the prognosis of these patients.
在我们的研究中，我们探讨了血清癌胚抗原（CEA）测定在结直肠癌患者中的价值。我们研究了56例年龄在40±16岁的结直肠癌患者，男女不限，其中26例有转移，30例无转移。结直肠癌患者血清CEA的阳性率在无转移患者中为66%（37/56），在有转移患者中为80.7%（21/26），在无转移患者中为53%（16/30）。血清CEA的参考值显著低于有转移和无转移的结直肠癌患者的血清CEA值（p1<0.001）。我们还注意到，有转移的结直肠癌患者的血清CEA值明显高于无转移的患者（p2<0.001）。分析结直肠癌患者的血清CEA值时，我们注意到我们研究中的所有血清CEA值≥20 ng/ml的患者都有转移。根据我们的数据，我们得出结论，结直肠癌患者血清CEA的测定对这些患者的诊断和预后非常有用。
