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[Quantitative assay of CD8+ (cytotoxic and suppressor) lymphocytes in patients with both asymptomatic and symptomatic HIV infection].

作者信息

Radkowski M, Laskus T, Kopicz-Kamińska E, Babiuch L, Slusarczyk J

机构信息

Zakładu Immunopatologii, Kliniki Nabytych Niedoborów Immunologicznych Instytutu Chorób Zakaźnych i Pasozytniczych, Warszawie.

出版信息

Pol Tyg Lek. 1992;47(36-37):787-9.

PMID:1293561
Abstract

Lymphocytes CD8+ have been assayed prospectively in 245 individuals infected with HIV. Percentage and number of CD8+ have been nearly two-fold higher in asymptomatic patients or patients with lymphadenopathy than those in the control group. The number of CD8+ lymphocytes has been rapidly decreasing parallel to the progression of HIV (ARC and AIDS), while their percentage has increased--however insignificantly. There has been a positive correlation between the number of CD4+ and CD8+ cells and all clinical stages of HIV infection.

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