Roberts Kari E, Hamele-Bena Diane, Saqi Anjali, Stein C A, Cole Randolph P
Division of Pulmonary, Allergy and Critical Care Medicine, New York, New York 10032, USA.
Am J Med. 2003 Aug 15;115(3):228-32. doi: 10.1016/s0002-9343(03)00305-x.
Dyspnea in a patient with cancer may have several causes, including infection, thromboembolism, metastases, and therapeutically induced cardiopulmonary disease. Pulmonary tumor embolism is an uncommon cause. Occlusion of the pulmonary microvasculature by tumor cells and associated thrombi can produce a subacute and progressive clinical picture that resembles thromboembolic disease. Unfortunately, microscopic tumor embolism is recognized rarely before death because of difficulty in establishing the diagnosis. We provide a review of the literature about the evaluation and diagnosis of this rare clinical entity.
癌症患者出现呼吸困难可能有多种原因,包括感染、血栓栓塞、转移以及治疗引起的心肺疾病。肺肿瘤栓塞是一种不常见的原因。肿瘤细胞和相关血栓阻塞肺微血管可产生类似于血栓栓塞性疾病的亚急性和进行性临床表现。不幸的是,由于难以确诊,显微镜下的肿瘤栓塞在死亡前很少被识别。我们对有关这种罕见临床实体的评估和诊断的文献进行了综述。