[4-氧代-4H-吡啶并(3',2':4,5)噻吩并(3,2-d)-1,3-恶嗪与胺的反应]
[Reactions of 4-oxo-4H-pyrido(3',2':4,5)thieno(3,2-d)-1,3-oxazines with amines].
作者信息
Böhm N, Krasselt U, Leistner S, Wagner G
机构信息
Fachbereich Biowissenschaften der Universität Leipzig, Germany.
出版信息
Pharmazie. 1992 Dec;47(12):897-901.
The reaction of the title compounds with amines gave in dependence of the reaction conditions and the structure of the title compounds and the amine 3-acylamino-thieno[2,3-b]pyridine-2-carbonamides (B), 4-oxo-4 H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidines (D),N-(2-carboxy-thieno[2,3-b]pyridine-3-yl)amidines (C) and N-(thieno[2,3-b]pyridin-3-yl)amidines (E). Substances of structure C and E seem to be of biological interest, especially for their antianaphylactic reactions.
标题化合物与胺的反应根据反应条件、标题化合物及胺的结构生成了3-酰氨基-噻吩并[2,3-b]吡啶-2-碳酰胺（B）、4-氧代-4H-吡啶并[3',2':4,5]噻吩并[3,2-d]嘧啶（D）、N-(2-羧基-噻吩并[2,3-b]吡啶-3-基)脒（C）和N-(噻吩并[2,3-b]吡啶-3-基)脒（E）。结构为C和E的物质似乎具有生物学意义，尤其是因其抗过敏反应。
Zotero 插件