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肽对视网膜和色素上皮细胞增殖活性的影响。

Effects of peptides on proliferative activity of retinal and pigmented epithelial cells.

作者信息

Khavinson V Kh, Zemchikhina V N, Trofimova S V, Malinin V V

机构信息

St. Petersburg Institute of Bioregulation and Gerontology, North-Western Division of Russian Academy of Medical Sciences, Moscow.

出版信息

Bull Exp Biol Med. 2003 Jun;135(6):597-9. doi: 10.1023/a:1025497806636.

Abstract

We studied the effects of Retinalamin (polypeptide preparation isolated from the retina) and a synthetic peptide Epithalon (Ala-Glu-Asp-Gly) on proliferative activity of retinal and pigmented epithelial cells. Experiments showed that Retinalamin and Epithalon (in certain concentrations) tissue-specifically stimulated proliferation of retinal and pigmented epithelial cell in culture.

摘要

我们研究了视网膜素(从视网膜分离出的多肽制剂)和合成肽埃皮塔隆(丙氨酸-谷氨酸-天冬氨酸-甘氨酸)对视网膜和色素上皮细胞增殖活性的影响。实验表明,视网膜素和埃皮塔隆(在特定浓度下)可特异性地刺激培养中的视网膜和色素上皮细胞增殖。

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