[原子吸收光谱法测定脑梗死患者头发中的锌、铜、镁和锰]

[Determination of Zn, Cu, Mg and Mn in hair of cerebral infarction by AAS].

作者信息

Zhao Wen-xiu, Li Yan

机构信息

Department of Chemistry of Jilin Military Medical College, Jilin 132013, China.

出版信息

Guang Pu Xue Yu Guang Pu Fen Xi. 2002 Jun;22(3):493-4.

PMID:12938346

Abstract

In order to study the relation between the contents of Zn, Cu, Mg and Mn in hair of 45 patients with cerebral infarction and 20 health people were determined by atomic absorption spectrometry (AAS). The results showed that the contents of Zn, Cu and Mg in the patients' hair (79.785 +/- 25.514, 8.241 +/- 1.405 and 24.831 +/- 9.986 respectively) were lower than that of the health people (168.031 +/- 29.467, 18.612 +/- 2.051 and 93.006 +/- 47.548 respectively) (p < 0.01), but the content of Mn of the patients (3.652 +/- 1.001) was higher than that of health people (1.751 +/- 0.597) (p < 0.01). These indicated that there must be some relation between the contents of Zn, Cu, Mg and Mn and the cerebral infarction. The lack of Zn, Cu and Mg as also as high level content of Mn subscribed to the formation of cerebral vascular deformation and sclerosis.

摘要

采用原子吸收光谱法（AAS）测定了45例脑梗死患者和20例健康人的头发中锌、铜、镁和锰的含量，以研究它们之间的关系。结果显示，患者头发中锌、铜和镁的含量（分别为79.785±25.514、8.241±1.405和24.831±9.986）低于健康人（分别为168.031±29.467、18.612±2.051和93.006±47.548）（p<0.01），但患者锰的含量（3.652±1.001）高于健康人（1.751±0.597）（p<0.01）。这些表明锌、铜、镁和锰的含量与脑梗死之间一定存在某种关系。锌、铜和镁的缺乏以及锰的高含量促成了脑血管变形和硬化的形成。