Pashchenkov M V, Pinegin B V, Link Kh, Boĭko A N
Zh Nevrol Psikhiatr Im S S Korsakova. 2003(Spec No 2):39-46.
Dendritic cells play a key role in initiation and regulation of adaptive immunity against pathogens and tumors, as well as in autoimmune disease. In this article we review recent data regarding distribution of dendritic cells in the central nervous system, their role in responses and possible role in pathogenesis of multiple sclerosis. We also consider possibilities to use dendritic cells as immunotherapeutic targets in multiple sclerosis.
树突状细胞在针对病原体和肿瘤的适应性免疫的启动和调节以及自身免疫性疾病中发挥关键作用。在本文中，我们综述了有关树突状细胞在中枢神经系统中的分布、它们在反应中的作用以及在多发性硬化症发病机制中可能作用的最新数据。我们还探讨了将树突状细胞用作多发性硬化症免疫治疗靶点的可能性。
