Lane Joshua E, Bowman Paul H, Cohen David J
Section of Dermatology, Department of Medicine, The Medical College of Georgia, Augusta, GA 30912, USA.
South Med J. 2003 Jun;96(6):613-5. doi: 10.1097/01.SMJ.0000054544.47233.7C.
Epidermodysplasia verruciformis is an uncommon cutaneous entity characterized by persistent human papillomavirus infection. A defect in cell-mediated immunity is the suggested causative factor. Numerous specific human papillomavirus types have been detected in this disease. Multiple nonmelanoma skin cancers are commonly seen in such patients; thus, early diagnosis is beneficial.
疣状表皮发育不良是一种罕见的皮肤疾病,其特征为持续性人乳头瘤病毒感染。细胞介导免疫缺陷被认为是致病因素。在该疾病中已检测到多种特定的人乳头瘤病毒类型。此类患者中常见多发性非黑色素瘤皮肤癌;因此,早期诊断有益。