Lipscombe Jennifer, Jassal Sarbjit V, Bailey Susan, Bargman Joanne M, Vas Stephen, Oreopoulos Dimitrios G
Division of Nephrology, University Health Network, Toronto, Ontario, Canada.
Perit Dial Int. 2003 May-Jun;23(3):255-9.
A multidisciplinary approach has been shown to be of benefit in the prevention of lower limb ulceration and amputation in patients with diabetes, but there is less information on the role of such an approach in patients receiving dialysis treatment.
The purpose of the present study was to determine whether the institution of a chiropody program would result in fewer amputations in diabetic patients on peritoneal dialysis (PD).
Retrospective chart review.
The PD program at a tertiary-care hospital.
Patients with diabetes that were enrolled in the PD program between January 1997 and December 1999, inclusive, that were offered the opportunity to see a chiropodist, and that agreed to be seen. A total of 132 patients were included.
Education about foot care, assessment, and, in some instances, treatment by a chiropodist.
Patients with an amputation were more likely to be male (p < 0.01) and have peripheral vascular disease (p < 0.001) compared to those without an amputation. They also had a lower average mean arterial pressure (p < 0.05), lower weekly creatinine clearance (p < 0.01), higher mean erythropoietin dose (p < 0.05), and longer duration of end-stage renal disease (p < 0.001). Factors that were predictive of shorter time to death or amputation were older age [hazard ratio (HR) = 1.03, p < 0.05], peripheral vascular disease (HR = 2.66, p< 0.01), and cerebrovascular disease (HR = 2.70, p< 0.01). Being seen by a chiropodist was protective (HR = 0.39, p < 0.01).
The current study suggests that a chiropody program may help to prevent amputation in patients with diabetes on PD.
多学科方法已被证明有助于预防糖尿病患者的下肢溃疡和截肢,但关于这种方法在接受透析治疗的患者中的作用的信息较少。
本研究的目的是确定实施足病治疗计划是否会减少接受腹膜透析(PD)的糖尿病患者的截肢率。
回顾性病历审查。
一家三级医院的PD项目。
1997年1月至1999年12月期间(含)参加PD项目、有机会看足病医生并同意就诊的糖尿病患者。共纳入132例患者。
足部护理教育、评估,在某些情况下由足病医生进行治疗。
与未截肢患者相比,截肢患者更可能为男性(p<0.01)且患有外周血管疾病(p<0.001)。他们的平均动脉压也较低(p<0.05),每周肌酐清除率较低(p<0.01),促红细胞生成素平均剂量较高(p<0.05),终末期肾病持续时间较长(p<0.001)。预测死亡或截肢时间较短的因素包括年龄较大[风险比(HR)=1.03,p<0.05]、外周血管疾病(HR=2.66,p<0.01)和脑血管疾病(HR=2.70,p<0.01)。接受足病医生诊治具有保护作用(HR=0.39,p<0.01)。
当前研究表明,足病治疗计划可能有助于预防接受PD治疗的糖尿病患者截肢。