对全身性HIV病毒载量抑制的反应与精神运动速度表现相关。
Response to systemic HIV viral load suppression correlates with psychomotor speed performance.
作者信息
Sacktor N, Skolasky R L, Tarwater P M, McArthur J C, Selnes O A, Becker J, Cohen B, Visscher B, Miller E N
机构信息
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
出版信息
Neurology. 2003 Aug 26;61(4):567-9. doi: 10.1212/01.wnl.0000076477.71313.6e.
The authors evaluated the association of a virologic response to highly active antiretroviral therapy, or a subsequent rebound, with performance on two measures of psychomotor speed in HIV-positive subjects. Virologic suppression was associated with improved performance on measures of psychomotor speed, and virologic rebound was associated with psychomotor speed performance decline. Changes in plasma HIV viral load in HIV-positive individuals with cognitive slowing correlate with performance on tests of psychomotor speed.
作者评估了高效抗逆转录病毒疗法的病毒学反应或随后的病毒反弹与HIV阳性受试者两项精神运动速度测量指标表现之间的关联。病毒学抑制与精神运动速度测量指标表现的改善相关，而病毒学反弹与精神运动速度表现下降相关。认知功能减慢的HIV阳性个体血浆HIV病毒载量的变化与精神运动速度测试的表现相关。
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