Drobiecki Arkadiusz, Kisiel Elzbieta, Wasińska Ewa
Dział Onkohematologii Swietokrzyskiego Centrum Onkologii w Kielcach, 25-734 Kielce, ul. Artwińskiego 3.
Przegl Lek. 2003;60(2):120-2.
Multiple myeloma is usually characterized by production of a single serum monoclonal protein of constant isotype and light chain restriction. Isotype switching in human lymphomas appears to be an uncommon event. It could be due to altered para-protein production by the malignant plasma cell clone, or oligoclonal Ig production during recovery of B-cell function after chemotherapy. We describe a case of clonal heavy chain isotype switching in a patient with lymphoplasmocytic lymphoma.
