Rao P Syamasundar, Gupta Monesha L, Balaji Seshadri
Division of Pediatric Cardiology, Department of Pediatrics, University of Texas-Houston Medical School, Memorial Hermann Children's Hospital, Houston, Texas 77030, USA.
Indian J Pediatr. 2003 Jul;70(7):557-64. doi: 10.1007/BF02723158.
Whereas the medical advances were reviewed in the previous paper, electrophysiological, transcatheter and surgical advances will be the focus in this review. Greater understanding of the arrhythmias, development of non-pharmacological treatment, namely catheter ablation and internal cardioverter-defibrillator (ICD) and miniaturization pacemakers and IDs have occurred in the last decade so that the methods could be applied to smaller and more complex patient population. Surgery has been the traditional treatment option for palliation and correction of congenital and acquired heart defects in infants and children. During the last one to one and one-half decades, a remarkable number of transcatheter methods were developed and refined. These developments during the last decade were reviewed and include long-term results of balloon dilatation procedures, transcatheter closure of atrial septal defects, patent ductus arteriosus, and ventricular septal defect, percutaneous valve replacement, intravascular stents to manage vascular obstructive lesions that can not be satisfactorily balloon-dilated, catheter completion of Fontan procedure, myocardial reduction in hypertrophic cardiomyopathy and other miscellaneous procedures. Recent advances in the transcatheter modes of therapy have added a new dimension to the management of neonates, infants and children with heart disease. They should now be added to the armamentarium available to the Pediatrician and Pediatric Cardiologist in the management of cardiac problems in the pediatric patient. Surgical methods and concepts have been greatly refined such that surgery can be undertaken even in the sickest and most complex patient. The majority of congenital heart defects can be corrected by open heart surgery; some require prior palliation and others can be operated without prior palliation. Recent advances in various defects were reviewed.
鉴于前一篇论文已对医学进展进行了综述,本文综述将聚焦于电生理、经导管及外科手术方面的进展。在过去十年中,人们对心律失常有了更深入的了解,非药物治疗得到了发展,即导管消融和植入式心脏复律除颤器(ICD),以及起搏器和植入式装置的小型化,从而使这些方法能够应用于更小且病情更复杂的患者群体。手术一直是治疗婴幼儿先天性和后天性心脏缺陷以缓解症状及进行矫正的传统选择。在过去的一到十五年间,大量经导管方法得到了开发和完善。本文回顾了过去十年间的这些进展,包括球囊扩张术的长期效果、经导管闭合房间隔缺损、动脉导管未闭和室间隔缺损、经皮瓣膜置换、用于处理无法通过球囊扩张得到满意治疗的血管阻塞性病变的血管内支架、经导管完成Fontan手术、肥厚型心肌病的心肌减容术以及其他各种手术。经导管治疗方式的最新进展为患有心脏病的新生儿、婴幼儿和儿童的治疗增添了新的维度。现在,它们应被纳入儿科医生和儿科心脏病专家用于治疗儿科患者心脏问题的手段之中。手术方法和理念已得到极大完善,以至于即使是病情最严重、最复杂的患者也能接受手术。大多数先天性心脏缺陷可通过心脏直视手术矫正;有些需要先进行姑息治疗,而另一些则可在无需先进行姑息治疗的情况下进行手术。本文还回顾了各种缺陷的最新进展。