Suppr超能文献

英国和爱尔兰孤立性先天性分流病变的手术和导管介入治疗趋势。

Trends in surgical and catheter interventions for isolated congenital shunt lesions in the UK and Ireland.

机构信息

Paediatric Cardiac Surgery, Birmingham Children's Hospital, Birmingham, UK.

Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.

出版信息

Heart. 2019 Jul;105(14):1103-1108. doi: 10.1136/heartjnl-2018-314428. Epub 2019 Feb 16.

Abstract

OBJECTIVE

To evaluate time trends in the use of catheter and surgical procedures, and associated survival in isolated congenital shunt lesions.

METHODS

Nationwide, retrospective observational study of the UK National Congenital Heart Disease Audit database from 2000 to 2016. Patients undergoing surgical or catheter procedures for atrial septal defect (including sinus venosus defect), patent foramen ovale, ventricular septal defect and patent arterial duct were included. Temporal changes in the frequency of procedures, and survival at 30 days and 1 year were determined.

RESULTS

40 911 procedures were performed, 16 604 surgical operations and 24 307 catheter-based interventions. Transcatheter procedures increased over time, overtaking surgical repair in 2003-2004, while the number of operations remained stable. Trends in interventions differed according to defect type and patient age. Catheter closure of atrial septal defects is now more common in children and adults, although surgical interventions have also increased. Patent foramen ovale closure in adults peaked in 2009-2010 before falling significantly since. Surgery remains the mainstay for ventricular septal defect in infants and children. Duct ligation is most common in neonates and infants, while transcatheter intervention is predominant in older children. Excluding duct ligation, survival following surgery was 99.4% and ≈98.7%, and following catheter interventions was 99.7% and ≈99.2%, at 30 days and 1 year, respectively.

CONCLUSIONS

Trends in catheter and surgical techniques for isolated congenital shunt lesions plot the evolution of the specialty over the last 16 years, reflecting changes in clinical guidelines, technology, expertise and reimbursement, with distinct patterns according to lesion and patient age.

摘要

目的

评估孤立性先天性分流病变的导管和手术治疗方法的应用趋势及其相关生存率。

方法

本研究为一项在英国国家先天性心脏病监测数据库中进行的回顾性、全国性观察性研究,时间跨度为 2000 年至 2016 年。纳入接受手术或导管治疗房间隔缺损(包括窦房缺损)、卵圆孔未闭、室间隔缺损和动脉导管未闭的患者。确定手术和导管治疗的频率随时间的变化以及术后 30 天和 1 年的生存率。

结果

共进行了 40911 次操作,其中 16604 次为手术,24307 次为导管介入治疗。经导管治疗的比例随时间推移而增加,于 2003-2004 年超过手术治疗,而手术数量则保持稳定。不同类型的缺损和患者年龄会导致干预措施的趋势有所不同。尽管手术治疗也有所增加,但现在儿童和成人中更常采用经导管关闭房间隔缺损。成人中卵圆孔未闭的封堵在 2009-2010 年达到峰值,此后显著下降。手术仍然是婴儿和儿童室间隔缺损的主要治疗方法。新生儿和婴儿中最常进行导管结扎,而大龄儿童中则以介入治疗为主。不包括导管结扎术,手术后 30 天和 1 年的生存率分别为 99.4%和≈98.7%,而经导管干预治疗后的生存率分别为 99.7%和≈99.2%。

结论

过去 16 年来,孤立性先天性分流病变的导管和手术治疗技术的趋势反映了该专业的发展演变,这与临床指南、技术、专业知识和报销制度的变化有关,不同病变和患者年龄的模式也不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edfa/6613741/21a53ed4b12a/heartjnl-2018-314428f01.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验