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Laryngotracheal growth following cricotracheal resection combined with laminotomy. An experimental study on rabbits.

作者信息

Weidenbecher Mark, Amann Kerstin, Iro Heinrich

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of of Erlangen-Nuremberg, Erlangen, Germany.

出版信息

Ann Otol Rhinol Laryngol. 2003 Aug;112(8):697-703. doi: 10.1177/000348940311200809.

DOI:10.1177/000348940311200809
PMID:12940668
Abstract

Cricotracheal resection (CTR) has been shown to be successful in the treatment of pediatric subglottic stenosis. Whether CTR combined with posterior midline division or partial resection of the cricoid plate affects the stability and growth of the larynx is still questionable. The study included 24 infant female New Zealand White rabbits that were divided into 4 groups of 6 animals each. Group 1 was the unoperated control group. Group 2 underwent removal of three quarters of the anterior cricoid circumference, followed by a primary anastomosis (CTR). In addition to CTR, the rabbits in group 3 underwent a laminotomy by splitting of the cricoid plate midline. Group 4 underwent both CTR and partial resection of the lamina. No stents were used in this study. After 6 months, the experiment was terminated, and the following observations were made. Groups 2 and 3 presented a large and stable subglottic lumen, comparable to that of the control group. After partial cricoid plate resection, 4 of the rabbits in group 4 suffered from a subglottic collapse that caused an airway obstruction and resulted in death. These results support the conclusion that CTR alone, as well as combined with laminotomy, can be performed in a relatively safe and effective manner without interfering with the development of the larynx in young rabbits. Cricotracheal resection together with partial resection of the cricoid plate, however, leads to an unstable situation with an impaired airway.

摘要

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引用本文的文献

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Experimental validation of laryngotracheal growth and recurrent laryngeal nerve preservation after partial cricotracheal resection in a growing rabbit model.生长兔模型中部分环状气管切除术后喉气管生长及喉返神经保留的实验验证
Pediatr Surg Int. 2018 Oct;34(10):1053-1058. doi: 10.1007/s00383-018-4314-5. Epub 2018 Jul 28.
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[Paediatric laryngotracheal stenosis: pattern of care in Germany].[小儿喉气管狭窄:德国的治疗模式]
HNO. 2006 Dec;54(12):929-36. doi: 10.1007/s00106-006-1398-3.