莱姆病螺旋体的群体感应

Quorum sensing by the Lyme disease spirochete.

作者信息

Stevenson Brian, von Lackum Kate, Wattier Rachel L, McAlister Jason D, Miller Jennifer C, Babb Kelly

机构信息

Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky College of Medicine, MS 415 Chandler Medical Center, Lexington, KY 40536-0298, USA.

出版信息

Microbes Infect. 2003 Sep;5(11):991-7. doi: 10.1016/s1286-4579(03)00184-9.

DOI:10.1016/s1286-4579(03)00184-9

PMID:12941391

Abstract

The Lyme disease spirochete, Borrelia burgdorferi, utilizes a LuxS/autoinducer-2-dependent quorum sensing mechanism to control a specific subset of bacterial proteins. It is hypothesized that this system facilitates transmission of B. burgdorferi from feeding ticks into warm-blooded hosts.

摘要

莱姆病螺旋体，伯氏疏螺旋体，利用一种依赖LuxS/自诱导物-2的群体感应机制来控制特定的细菌蛋白子集。据推测，该系统有助于伯氏疏螺旋体从进食的蜱虫传播到温血宿主中。